Dr Ann L Lee

Areas of Interest:
Developing purification processes for vaccines, therapeutic proteins (monoclonal antibodies), natural products and biocatalysis intermediates - scope includes creative process design/development cGMP production, scale up, process validation and process transfer/start-up. Specific unit operations: chromatography (AEX, CEX, RP, EBA, SEC, hydroxyapitite, affinity, membrane chromatography) membrane filtration, precipitation, crystillization, enzymatic reactions, centrifugation, extractions and new downstream purification technologies. Other areas of interest: process monitoring assays, high throughput analytical assays/laboratory automation, miniaturization of unit operations and equipment. General interest - vaccines, microbial fermentation, biotechnology technologies.